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Ionis Pharmaceuticals, Inc. (IONS) Stock Forecast

Data as of Oct 31, 2026

Healthcare · Current price $43.41 (-2.21%)

Consensus Target
$84.08
Upside
+95.6%
Analysts
35
Rating
Buy(2.17)

Price Target Range

Low $54.00Consensus $84.08High $115.00
▲ Current $43.41

Consensus Price Target Over Time

Analyst Rating Distribution

Last 3 Months

Consensus
Buy
Strong Buy0
Buy13
Hold4
Sell0
Strong Sell0

6-Month Trend

Latest Analyst Forecasts

Price targets issued by Wall Street analysts. Upside calculated against today's price.

DateAnalystFirmPrice TargetUpside
Apr 10, 2026Tiago FauthRaymond James$104.00+139.6%
Feb 25, 2026Michael UlzMorgan Stanley$95.00+118.8%
Dec 17, 2025Luca IssiRBC Capital$95.00+118.8%
Oct 8, 2025Justin KimOppenheimer$90.00+107.3%
Sep 23, 2025Gena WangBarclays$82.00+88.9%
Sep 22, 2025Gary NachmanRaymond James$75.00+72.8%
Sep 3, 2025Kostas BiliourisBMO Capital$70.00+61.3%
Sep 2, 2025Gena WangBarclays$78.00+79.7%
Sep 2, 2025Michael UlzMorgan Stanley$71.00+63.6%
Sep 2, 2025Mitchell KapoorH.C. Wainwright$95.00+118.8%
Aug 22, 2025Yanan ZhuWells Fargo$82.00+88.9%
Oct 9, 2024Debjit ChattopadhyayGuggenheim$65.00+49.7%
Aug 2, 2024Kostas BiliourisBMO Capital$60.00+38.2%
Jul 24, 2024Mani ForooharLeerink Partners$62.00+42.8%
Jul 22, 2024Akash TewariJefferies$77.00+77.4%
Jul 22, 2024Salveen RichterGoldman Sachs$33.00-24.0%
Jul 16, 2024Akash TewariJefferies$75.00+72.8%
Jun 27, 2024Paul MatteisStifel Nicolaus$53.00+22.1%
Jun 17, 2024Luca IssiRBC Capital$70.00+61.3%
Jun 14, 2024William PickeringTudor Pickering$44.00+1.4%

IONS vs Sector & Market

MetricIONSHealthcare AvgLarge Cap Avg
Analyst Rating2.172.252.41
Analyst Count35819
Target Upside+95.6%+153002.0%+21.5%
P/E Ratio-30.523.5038.49

Revenue Estimates

PeriodLowAvgHigh#
2026-12-31$191M$244M$279M5
2027-03-31$208M$265M$303M5
2027-06-30$242M$309M$353M5
2027-09-30$288M$367M$419M5
2027-12-31$351M$447M$511M5
2028-12-31$2.01B$2.02B$2.02B14
2029-12-31$2.33B$2.75B$3.26B9
2030-12-31$3.02B$3.56B$4.22B13

EPS Estimates

PeriodLowAvgHigh#
2026-12-31$-1.16$-0.98$-0.701
2027-03-31$-0.38$-0.32$-0.231
2027-06-30$-0.25$-0.21$-0.151
2027-09-30$-0.06$-0.05$-0.041
2027-12-31$0.09$0.12$0.141
2028-12-31$-3.77$1.17$5.0210
2029-12-31$2.91$3.63$4.504
2030-12-31$5.19$6.47$8.034

Frequently Asked Questions

What is the analyst consensus for IONS?

The consensus among 35 analysts covering Ionis Pharmaceuticals, Inc. (IONS) is Buy with an average price target of $84.08.

What is the highest price target for IONS?

The highest price target for IONS is $104.00, set by Tiago Fauth at Raymond James on 2026-04-10.

What is the lowest price target for IONS?

The lowest price target for IONS is $30.00, set by Jason Gerberry at Bank of America Securities on 2022-02-01.

How many analysts cover IONS?

35 analysts have issued ratings for Ionis Pharmaceuticals, Inc. in the past 12 months.

Is IONS a buy or sell right now?

Based on 35 analyst ratings, IONS has a consensus rating of Buy (2.17/5) with a +95.6% upside to the consensus target of $84.08.

What are the earnings estimates for IONS?

Analysts estimate IONS will report EPS of $-0.98 for the period ending 2026-12-31, with revenue estimated at $244M.

Data updated daily. Analyst price targets sourced from public filings and broker reports. Not investment advice.